uricol drug 00000Uricol plus for treatment of gout and urolithiasis

Uricol plus for treatment of gout and urolithiasis
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uricol drug 00000Uricol plus for treatment of gout and urolithiasis Uricol11

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URICOL PLUS
For Treatment of Gout and Urolithiasis
Effervescent Granules SUGAR FREE

Composition:

Each sachet ( 5 g) contains:
Piperazine citrate 195 mg
Khellin 1.83 mg
Colchicine 0.30 mg
Effervescent base to 5 g

Properties:

URICOL PLUS is a multifunctional balanced fomnulation combining three active
ingredients with antigout, urinary antispasmodic and urate antilithic effects.
Cok:hicine is a potent antigout that relieves the manifestations of acute gouty
arthritis. Colchicine acts by Inhibiting the formation and release of the glycoprotein that causes joint pain and inflammation during phagocytosis of urate crystals. Colchicine is also effective in decreasing the frequency and severity of acute attacks when taken prophylactically in chronic gout. Khellin, the second ingredient in URICOL PLUS, is a powertul antispasmodic. Khellin relieves urinary smooth muscle spasm and hypermotility associated with the irritation due to urate crystals. Piperazine citrate, the third ingredient in URICOL PLUS, adjusts the pH of urine to the appropriate value for dissolution and prevention of the deposition of urate crystals. These properties demonstrate the superiority of URICOL PLUS as potent antigout with high efficacy in treatment of urinary tract spasm and prevention of urate lithiasis. Also, the formulation of URICOL PLUS in effervescent granules makes its
taste pleasant and palatable and its absorption rapid with fast onset of action.

Indications:

– Acute gouty arthritis, to relieve pain and inflammation.
– Chronic gout, as prophylaxis against acute attacks.
– As an adjunct therapy to reduce frequency 01 acute gouty attacks and during’
treatment with allopurinol and uricosurics.
– Prevention of urate stone formation.

Dosage :

The contents of one sachet is added to half a glass of water and taken during effervescence
– acte gouty arthritis : chets every 2 to 3 hours until the ain disappears. If GI side effects occur, the treatment should be discontinued.
– Chronic gout: 1-2 sachets once or twice daily or as directed by the physician.
– Prophylaxis against urate stones: as in chronic gout.

Contraindlcatlons:

Hypersensitivity to any component of URICOL PLUS, and severe renal impaimnent.

Precautions:

URICOL PLUS is used cautiously in patients with renal, hepatic, cardiac or GI
problems.

Side effects:

URICOL PLUS is safe and well tolerated. GI disturbances, e.g. nausea, vonniting,
diarrhea and abdominal pain, may occur.

Pregnancy alftllactatlon :

Medications containing colchicine are not recommended for use during pregnancy and lactation.

Drug interactions:

Concomitant” use of cyclosporin with colchicine may increase the risk of myopathies. The use of erythronnycin with colchicine for more than 2
weeks in patients with hepatic and renal marrow depressants and radiotherapy with colchicine increases the incidence of bone
marrow depression.

Interference with laboratory tests:

None reported.

Overdosage and treatment:

None reported.

Packing:

A baxcontaining 6 or 12 sachets (5 g each).

Storage :

– Store at temperature (15 – 25· C),away Irom moisture.
– Keep out of the reach 01 children.

manufactured by :

Council of Arab Health Ministers,
Union of Arab Pharmacists.
Made In Egypt
Pharmacuticals
AI.exandria

[size=24][size=24]What is Uricol?
Uricol granules is used for Roundworm infections, Pinworm infections, Urinary tract infections, Angina pectoris, Asthma, Vitiligo, Ultraviolet irradiation, Threadworm infections and other conditions. Uricol granules may also be used for purposes not listed in this medication guide.
Uricol granules contains Hexamine, Khellin and Piperazine as active ingredients.
Uricol granules works by stopping the growth of unwanted bacteria; producing vasodilator and bronchodilator action; producing a neuromuscular block leads to muscle paralysis of the worms;
Pharco manufactures Uricol granules.
Detailed information related to Uricol granules's uses, composition, dosage, side effects and reviews is listed below.

Uricol granules Uses
Uricol granules is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
Roundworm infections
Pinworm infections
Urinary tract infections
Angina pectoris
Asthma
Vitiligo
Ultraviolet irradiation
Threadworm infections
Uricol granules may also be used for purposes not listed here.
References: 1, 2, 3
Learn more: Uses

Uricol granules - Composition and Active Ingredients
Uricol granules is composed of the following active ingredients (salts)
Hexamine
Khellin
Piperazine
Please note that this medicine may be available in various strengths for each active ingredient listed above.
Uricol granules - Side-effects
The following is a list of possible side-effects that may occur from all constituting ingredients of Uricol granules. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
Dysuria
Rash
Nausea
Pruritis
Pyuria
Vomiting
Upset stomach
Jerky movement
Muscular incoordination
Feeling of sickness
Uricol granules may also cause side-effects not listed here.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
References: 1, 4
Learn more: Side-effects
Uricol granules Working, Mechanism of Action and Pharmacology
Uricol granules improves the patient's condition by performing the following functions:
Stopping the growth of unwanted bacteria.
Producing vasodilator and bronchodilator action.
Producing a neuromuscular block leads to muscle paralysis of the worms.
References: 1, 2, 5

Uricol granules - Precautions & How to Use
Before using Uricol granules, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
Consult a doctor if you have hepatic impairment
Lactation
do not swallow
References: 2
Learn more: Precautions & How to Use

Uricol granules - Drug Interactions
If you use other drugs or over the counter products at the same time, the effects of Uricol granules may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Uricol granules may interact with the following drugs and products:
Bephenium Hydroxynaphthoate
Chlorpromazine
Methotrimeprazine
Pyrantel Pamoate
Sulfamethizole
Sulfathiazole
Sulpiride
Thiazides
References: 1
Learn more: Interactions
Uricol granules - Contraindications
Hypersensitivity to Uricol granules is a contraindication. In addition, Uricol granules should not be used if you have the following conditions:
Epilepsy
Severe renal impairment
hepatic insufficiency
renal insufficiency
severe dehydration
Learn more: Contraindications

Uricol granules - Frequently asked Questions
Is Uricol granules safe to consume or apply when pregnant?
Hexamine: Please consult with your doctor for case-specific recommendations.
Khellin: Please consult with your doctor for case-specific recommendations.
Piperazine: Please consult with your doctor for case-specific recommendations.
References: 1
Is Uricol granules safe while breastfeeding?
Hexamine: No
Khellin: Please discuss the risks and benefits with your doctor.
Piperazine: Please discuss the risks and benefits with your doctor.
References: 1
Can Uricol granules be used for roundworm infections and pinworm infections?
Yes, roundworm infections and pinworm infections are among the most common reported uses for Uricol granules. Please do not use Uricol granules for roundworm infections and pinworm infections without consulting first with your doctor. Click here and view survey results to find out what other patients report as common uses for Uricol granules.
Is it safe to drive or operate heavy machinery when consuming?
If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Uricol granules medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Uricol granules. Always consult with your doctor for recommendations specific to your body and health conditions.
Is this medicine or product addictive or habit forming?
Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.
Can it be stopped immediately or do I have to slowly ween off consumption?
Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

Other important Information on Uricol granules
Missing a dose
In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
References: 6, 7, 8, 9
Overdosage of Uricol granules
Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Uricol granules, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
Please consult your physician or pharmacist or product package for more information.
References: 10, 11, 12
Storage of Uricol granules
Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Uricol granules.
References: 13, 14, 15, 16
Expired Uricol granules
Taking a single dose of expired Uricol granules is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
References: 17, 18
Dosage Information
Please consult your physician or pharmacist or refer to product package.
Uricol granules - Packages and Strengths
Uricol granules is available in the following packages and strengths
Uricol granules - Packages: 6 sachet
Uricol granules - Manufacturers
The medicine is manufactured by the following companies
Pharco

Pharco
References
Pubchem Methenamine https://pubchem.ncbi.nlm.nih.gov/compoun... - Accessed: October 12, 2016.
Pubchem Khellin https://pubchem.ncbi.nlm.nih.gov/compoun... - Accessed: October 12, 2016.
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006. from HSDB Record Name: PIPERAZINE http://toxnet.nlm.nih.gov?dbs+hsdb:@term... - Accessed: October 12, 2016.
Clayton, G. D. and F. E. Clayton (eds.). Patty's Industrial Hygiene and Toxicology: Volume 2A, 2B, 2C: Toxicology. 3rd ed. New York: John Wiley Sons, 1981-1982., p. 2692 Source: HSDB Record Name: PIPERAZINE http://toxnet.nlm.nih.gov?dbs+hsdb:@term... - Accessed: October 12, 2016.
Thomson/Micromedex. Drug Information for the Health Care Professional. Volume 1, Greenwood Village, CO. 2006. Source: HSDB Record Name: PIPERAZINE http://toxnet.nlm.nih.gov?dbs+hsdb:@term... - Accessed: October 12, 2016.
NHS Choices. What should I do if I miss a dose of antibiotics? - Accessed: July 14, 2016.
Ever Miss a Dose of Your Medicine? - Accessed: July 3, 2016.
Cancer.Net (2014). The Importance of Taking Your Medication Correctly - Accessed: July 3, 2016.
Schachter, S.C., Shafer, P. O. &; Sirven, J.I. (2013). Missed Medicines. Epilepsy Foundation - Accessed: May 28, 2016.
National Institute of Drug Abuse (2010). Prescription Drugs: Abuse and Addiction. Report Research Series - Accessed: July 21, 2016.
eMedicinehealth (2016). Drug Overdose Overview - Accessed: July 21, 2016.
Centers for Disease Control and Prevention (2010). Unintentional drug poisoning in the United States - Accessed: July 21, 2016.
Centers for Disease Control and Prevention. December 12, 2011. Put your medicines up and away and out of sight - Accessed: June 10, 2016.
The Center for Improving Medication Management and the National Council on Patient Information and Education. The quick scoop: medicines and your family: safely storing and disposing of medicines - Accessed: June 10, 2016.
U.S. Food and Drug Administration. December 24, 2013. How to dispose of unused medications - Accessed: June 10, 2016.
World Health Organization: Information sheet: Pharmaceuticals in drinking-water - Accessed: July 1, 2016.
Lyon, R. C., Taylor, J. S., Porter, D. A., et al. (2006) Stability profiles of drug products extended beyond labeled expiration dates. Journal of Pharmaceutical Sciences; 95:1549-60 - Accessed: July 3, 2016.
Harvard Medical School (2016). Drug Expiration Dates - Do They Mean Anything? - Accessed: May 1, 2016.
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Related Links
Uricol granules for roundworm infections
Uricol granules for pinworm infections
More about Uricol granules
Uses
Side-effects
Composition
Interactions
Contraindications
Precautions
Reviews
Questions
Last updated date
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Uricol for urinary antiseptic, antispasmodic and for urinary lithiasis

URICOL Effervescent Granules
Urinary Antiseptic, Antispasmodic & For Urinary Lithiasis

Composition:

Each sache1 (5 g) contains:
Hexamine 500.00 mg
Piperazine citrate 190.00 mg
Khellin 1.83 mg
Effervescen1 base 10 5.00g

Properties :

URICOl is a multifunctional formulation combining three active ingredients, each complementing the other wi1h potent urinary antiseptic, antispasmodic and anlililhic effects. Hexamine, the first il1!)redienl in URICOL, is an antiseptic that prevents and treats urinary tract infections and asymptomatic bactenuria. In acidic urine, hexamine is hydrolyzed to formaldehyde which exerts potent antimicrobial effect against Gram-positive and Gram-negative bacteria and fungi. Hexamine is safe for lOng-term use and no emergence of resistance occurs. Piperazine citrate, the second ingredient in URICO’L, adjusts the pH of urine to the appropriate value that helps dissolve uric acid and prevents formation and deposition of urate calculi. Khellin, the third ingredient in
URICOL, is a powerful antispasmodic that relieves urinary smooth muscle spasm and hypermotility associated with infection, diagnostic procedures or irritations due to calculi. These properties demonstrate the superior antiseptic effects of URICOL and its h~h efficacy in relievir19 and overcoming urinary tract spasm, and reventing formation and deposition of unnary calculi. FormulatIOn of URICOL in single dose (5 g) sachets, ensures pleasant taste and rapid absorption with fast onset of action.

Indications:

– Chronic urinary tract infections, as in pyelitis, pyelonephritis, cystitis and infections accompanying neurogenic bladder.
– As a prophylaxis against urinary tract infection in patients with residual urine due to different causes including neuroloical ctseasss.os-proonqed bladder catheterization.
– fast relif of urinary tract spasms and irritations caused by crystalluria and urinary calculi
– Prevention of urinary tract lithiasis.

Dosage and mode of administration:

The contents of one URICOL sachet is added to half a glass of water and taken during effervescence.
Chronic urinary tract infections, spasms of the urinary tract and prevention of urinary tract lithiasis: 1-2 sachets to be taken 3 – 4 times daily or as directed by the physician.
Indications:

– Chronic urinary tract infections, as in pyelitis, pyelonephritis, cystitis and infections accompanying neurogenic bladder.
– As a prophylaxis against urinary tract infection in patients with residual urine due to different causes including neuroloical ctseasss.os-proonqed bladder catheterization.
– fast relif of urinary tract spasms and irritations caused by crystalluria and urinary calculi
– Prevention of urinary tract lithiasis.

Dosage and mode of administration:

The contents of one URICOL sachet is added to half a glass of water and taken during effervescence.
Chronic urinary tract infections, spasms of the urinary tract and prevention of urinary tract lithiasis: 1-2 sachets to be taken 3 – 4 times daily or as directed by the physician.
Contraindications :

Hypersensitivity to any component of URICOL, severe hepatic diseases and renal insufficiency.

precautions :

Hexamine containing prepartions should not be given to patients
taking sulfonamides to avoid formation of insoluble precipitates in urinary tract

Side effects :

URICOL is safe and well tolerated with almost no side effects However nausea, stomach upset Of rash might rarely occur.

pregnancy and lactation :

medications containing hexamine should be taken under medical .
supervision during pregnancy and lactation.

Drug interactions:

Concomitant ad.mlnistratiOn of hexamine with sulfonamides results In mutual antagomsm.

Interference with laboratory tests:

None reported.

Overdosage and treatment :
None reported with effervescent formulations.

Packing :

A box containing 6 or 12 sachets (5 9 each).

storage :

keep at tempera1ure (15· 3o C), away from moisture.
Keep oul of Ihe reach of children.

produced by :

pharco pharmaceuticals

Causes of dysuria
Urinary tract infection. Share on Pinterest A UTI can make urination painful. ...
Sexually transmitted infection. ...
Prostate infection. ...
Kidney stones. ...
Ovarian cysts. ...
Interstitial cystitis. ...
Chemical sensitivity. ...
Vaginal infection or irritation.

What can make urination painful
Kidney stones (also called renal calculi, nephrolithiasis or urolithiasis) are hard deposits made of minerals and salts that form inside your kidneys.

Diet, excess body weight, some medical conditions, and certain supplements and medications are among the many causes of kidney stones. Kidney stones can affect any part of your urinary tract — from your kidneys to your bladder. Often, stones form when the urine becomes concentrated, allowing minerals to crystallize and stick together.

Passing kidney stones can be quite painful, but the stones usually cause no permanent damage if they're recognized in a timely fashion. Depending on your situation, you may need nothing more than to take pain medication and drink lots of water to pass a kidney stone. In other instances — for example, if stones become lodged in the urinary tract, are associated with a urinary infection or cause complications — surgery may be needed.

Your doctor may recommend preventive treatment to reduce your risk of recurrent kidney stones if you're at increased risk of developing them again.

Products & Services
Book: Mayo Clinic Book of Home Remedies
Symptoms
Illustration showing kidney stones
Kidney stonesOpen pop-up dialog box
A kidney stone usually will not cause symptoms until it moves around within your kidney or passes into your ureters — the tubes connecting the kidneys and the bladder. If it becomes lodged in the ureters, it may block the flow of urine and cause the kidney to swell and the ureter to spasm, which can be very painful. At that point, you may experience these signs and symptoms:

Severe, sharp pain in the side and back, below the ribs
Pain that radiates to the lower abdomen and groin
Pain that comes in waves and fluctuates in intensity
Pain or burning sensation while urinating
Other signs and symptoms may include:

Pink, red or brown urine
Cloudy or foul-smelling urine
A persistent need to urinate, urinating more often than usual or urinating in small amounts
Nausea and vomiting
Fever and chills if an infection is present
Pain caused by a kidney stone may change — for instance, shifting to a different location or increasing in intensity — as the stone moves through your urinary tract.

When to see a doctor
Make an appointment with your doctor if you have any signs and symptoms that worry you.

Seek immediate medical attention if you experience:

Pain so severe that you can't sit still or find a comfortable position
Pain accompanied by nausea and vomiting
Pain accompanied by fever and chills
Blood in your urine
Difficulty passing urine

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Causes
Kidney stones often have no definite, single cause, although several factors may increase your risk.

Kidney stones form when your urine contains more crystal-forming substances — such as calcium, oxalate and uric acid — than the fluid in your urine can dilute. At the same time, your urine may lack substances that prevent crystals from sticking together, creating an ideal environment for kidney stones to form.

Types of kidney stones
Knowing the type of kidney stone you have helps determine its cause, and may give clues on how to reduce your risk of getting more kidney stones. If possible, try to save your kidney stone if you pass one so that you can bring it to your doctor for analysis.

Types of kidney stones include:

Calcium stones. Most kidney stones are calcium stones, usually in the form of calcium oxalate. Oxalate is a substance made daily by your liver or absorbed from your diet. Certain fruits and vegetables, as well as nuts and chocolate, have high oxalate content.

Dietary factors, high doses of vitamin D, intestinal bypass surgery and several metabolic disorders can increase the concentration of calcium or oxalate in urine.

Calcium stones may also occur in the form of calcium phosphate. This type of stone is more common in metabolic conditions, such as renal tubular acidosis. It may also be associated with certain medications used to treat migraines or seizures, such as topiramate (Topamax, Trokendi XR, Qudexy XR).

Struvite stones. Struvite stones form in response to a urinary tract infection. These stones can grow quickly and become quite large, sometimes with few symptoms or little warning.
Uric acid stones. Uric acid stones can form in people who lose too much fluid because of chronic diarrhea or malabsorption, those who eat a high-protein diet, and those with diabetes or metabolic syndrome. Certain genetic factors also may increase your risk of uric acid stones.
Cystine stones. These stones form in people with a hereditary disorder called cystinuria that causes the kidneys to excrete too much of a specific amino acid.
Risk factors
Factors that increase your risk of developing kidney stones include:

Family or personal history. If someone in your family has had kidney stones, you're more likely to develop stones, too. If you've already had one or more kidney stones, you're at increased risk of developing another.
Dehydration. Not drinking enough water each day can increase your risk of kidney stones. People who live in warm, dry climates and those who sweat a lot may be at higher risk than others.
Certain diets. Eating a diet that's high in protein, sodium (salt) and sugar may increase your risk of some types of kidney stones. This is especially true with a high-sodium diet. Too much salt in your diet increases the amount of calcium your kidneys must filter and significantly increases your risk of kidney stones.
Obesity. High body mass index (BMI), large waist size and weight gain have been linked to an increased risk of kidney stones.
Digestive diseases and surgery. Gastric bypass surgery, inflammatory bowel disease or chronic diarrhea can cause changes in the digestive process that affect your absorption of calcium and water, increasing the amounts of stone-forming substances in your urine.
Other medical conditions such as renal tubular acidosis, cystinuria, hyperparathyroidism and repeated urinary tract infections also can increase your risk of kidney stones.
urocol treatment
Certain supplements and medications, such as vitamin C, dietary supplements, laxatives (when used excessively), calcium-based antacids, and certain medications used to treat migraines or depression, can increase your risk of kidney stones.

By Mayo Clinic Staff
Kidney stones care at Mayo Clinic

Request an Appointment at Mayo Clinic
Diagnosis & treatment
May 05, 2020PrintShare on: FacebookTwitter
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Related
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Preventing Kidney Stones
Associated Procedures
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Mayo Clinic Minute: What you can eat to help avoid getting kidney stones
Sept. 09, 2021, 03:00 p.m. CDT
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Products & Services
A condition affecting the bladder or nearby parts of the body can cause painful urination. Doctors may also refer to painful urination as dysuria.

Multiple potential causes for this symptom exist, and many of them are treatable.

People with dysuria should make their doctor aware of any other symptoms that they are experiencing. If these relate to the painful urination, it can help doctors make a diagnosis and recommend appropriate treatment.

Causes of dysuria
Many different conditions can cause painful urination. Most of these causes are highly treatable.

Below are 10 possible causes of painful urination, along with other symptoms that may occur alongside it.

1. Urinary tract infection
A urinary tract infection (UTI) occurs when excess bacteria build up somewhere in the urinary tract. This part of the body runs from the kidneys to the bladder to the urethra, which carries urine toward the outside of the body.

Additional symptoms

A person with a UTI may experience other symptoms, such as:

needing to urinate frequently
passing cloudy or blood-tinged urine
fever
foul-smelling urine
pain in the side and back
2. Sexually transmitted infection
Sexually transmitted infections (STIs), such as chlamydia, gonorrhea, and herpes, can all affect the urinary tract and lead to pain when urinating.

Additional symptoms

Symptoms may vary according to the type of STI. For example, herpes typically causes blister-like lesions on the genitals.

3. Prostate infection
A short-term bacterial infection can result in a prostate infection or prostatitis. Chronic inflammation from another condition, such as an STI, can also cause prostatitis.

Additional symptoms

A prostate infection may also cause:

difficulty urinating
pain in the bladder, testicles, and penis
difficulty ejaculating and painful ejaculation
needing to urinate frequently, especially at night
4. Kidney stones
Kidney stones are collections of materials, such as calcium or uric acid, that build up and form hardened stones in and around the kidneys.

Sometimes, the kidney stones will lodge themselves near the area where urine enters the bladder. This can cause painful urination.

Additional symptoms

In addition to dysuria, kidney stones can cause the following symptoms:

pain in the side and back
pink- or brown-tinted urine
cloudy urine
nausea
vomiting
pain that changes in intensity
fever
chills
urinating only small amounts frequently
5. Ovarian cysts
Much like kidney stones, ovarian cysts are an example of how something outside the bladder can press on it and cause painful urination.

Ovarian cysts can develop on one or both ovaries, which sit on either side of the bladder.

Additional symptoms

People with ovarian cysts may experience:

unusual vaginal bleeding
pelvic pain
difficulty recognizing that the bladder is empty after urinating
painful periods
breast tenderness
a dull ache in the lower back
6. Interstitial cystitis
Also known as bladder pain syndrome, interstitial cystitis is a condition that causes chronic irritation of the bladder lasting 6 weeks or more without an underlying infection.

Additional symptoms

Interstitial cystitis may also cause the symptoms below:

pressure in the bladder area
pain during intercourse
pain in the vulva or vagina
pain in the scrotum
urinating frequently but producing little urine
7. Chemical sensitivity
Sometimes, chemicals that are external to the body, such as fragrances, can irritate bodily tissues. When a person urinates, this irritation may be more noticeable, and pain may occur.

Products that can cause chemical sensitivity include:

douches
soaps
scented toilet paper
vaginal lubricants
contraceptive foams
Additional symptoms

People who react to chemical products may notice:

swelling
redness
itching
irritation of the skin on or around the genitals
8. Vaginal infection or irritation
Also known as vaginitis or vaginosis, a vaginal infection can occur due to the overgrowth of bacteria or yeast.

An STI called trichomoniasis can also cause a vaginal infection.

Additional symptoms

The following symptoms may occur alongside painful urination:

foul-smelling or unusual vaginal discharge
vaginal irritation
pain during intercourse
vaginal bleeding, which is usually mild
9. Medication
Some medications, including those that doctors prescribe to treat bladder cancer, may irritate and inflame the bladder tissues. This can often cause pain when urinating.

If a person has started a new medication and begins to feel pain when urinating, they should call their doctor and ask if the symptom may be a side effect of the drug. They should not stop taking the medication on their own without asking a doctor first.

Additional symptoms

Additional symptoms vary based on the type of medication.

10. Bladder cancer
Bladder cancer occurs when cancer cells start to develop in the bladder.

Feeling pain when urinating is not typically an early symptom of this condition. Instead, a person usually notices blood in their urine.

Additional symptoms

Other possible symptoms of bladder cancer include:

frequent urination
having difficulty urinating or passing a weak urine stream
lower back pain
appetite loss
weight loss
fatigue
foot swelling
bone pain
Differences in males and females
Males and females can both experience pain when urinating, and the causes may be anatomy-dependent.

For example, females have shorter urethras than males. As a result, bacteria can often enter the bladder more easily, which can lead to UTIs.

A person can talk to their doctor about their risks for painful urination based on their sex as well as their medical history.

When to see a doctor
Everyone may experience painful urination from time to time.

A person should see their doctor if the pain is consistent, and they are also experiencing the following symptoms:

blood in the urine, which will usually appear pink, brown, or red
pain in the side or back
pain that lasts longer than 24 hours
unusual discharge from the penis or vagina
fever
If an adult has a fever that is higher than 103°F, they should seek emergency medical attention.

A person should not ignore pain when urinating. A doctor can often help identify treatments that will reduce pain.

Potential treatment options
Treatment options for painful urination depend on the underlying cause. Some examples include:

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Treating UTIs with antibiotics. Severe UTIs that affect the kidneys may require intravenous antibiotics.
Treating prostatitis with antibiotics. A person may take these for up to 12 weeks if they have chronic bacterial prostatitis. Other possible prostatitis treatments include over-the-counter (OTC) anti-inflammatories, prostatic massage, hot baths, and medications called alpha-blockers, which relax the muscles around the prostate.
Avoiding the use of harsh soaps or other chemical products near the genitals that could potentially lead to irritation. A person’s symptoms will often resolve quickly when chemical irritation is the underlying cause.
At-home care for painful urination often includes taking OTC anti-inflammatory medications, such as ibuprofen.

A doctor will often encourage a person to drink more fluids as this dilutes urine, making it less painful to pass. Resting and taking medications as directed can usually help relieve most symptoms.

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Causes of dysuriaUrinary tract infection. Share on Pinterest A UTI can make urination painful. ...Sexually transmitted infection. ...Prostate infection. ...Kidney stones. ...Ovarian cysts. ...Interstitial cystitis. ...Chemical sensitivity. ...Vaginal infection or irritation.

Causes of dysuria
Urinary tract infection. Share on Pinterest A UTI can make urination painful. ...
Sexually transmitted infection. ...
Prostate infection. ...
Kidney stones. ...
Ovarian cysts. ...
Interstitial cystitis. ...
Chemical sensitivity. ...
Vaginal infection or irritation.